Endocrine Abstracts

Introduction: Cushing disease (CD) is a condition due to an ACTH-secreting pituitary adenoma that is usually a microadenoma. Seldom, the lesion may be atypical by his size or his radiological aspect.The aim of this study is to analyze the clinical and biological data of CD with atypical radiological aspect (macroadenoma or other), to compare them to those of CD with a typical radiological aspect (microadenoma) and to determine the clinical or biological ...

Objective: The objective of this study was to examine the factors influencing the severity of hepatic steatosis in type 2 diabetes.Methods: Computed tomography imaging was used to assess hepatic fat content in 80 men and women with type 2 diabetes. Inclusion criteria included a confirmed diagnosis of type 2 diabetes (≥1 year of duration), without history of hepatic disease or daily consumption of alcohol drink. The ratio of liver to spleen attenuat...

The overall incidence of carcinoid tumors has been estimated to be 1 to 2 cases /100000 people in USA. Carcinoid tumors habitually accounts for 1% of all cases of Cushing’s syndrome. The authors report an unusual case of ectopic secretion of corticotropin from pulmonary carcinoid tumor.A. F. is a 29 years old patient who has been referred for hypercorticism with patent features including trophical signs and severe depression.L...

Pituitary enlargement with long standing hypothyroidism is well established.The clinical evolution of pituitary hyperplasia to thyroid hormone should be monitored closely during primary hypothyroidism because of the rare possibility of an incidental non thyrotropic pituitary tumor that will not regress on thyroid hormone. We report a case of a pituitary mass not responding to thyroid hormone therapy.A 46 years old women was admitte...

Most macroprolactinomas are responsive to dopamine against drugs. Bromocriptine (BRC) has been available and extensively used in our country. The aims are to assess the outcome in 29 patients with macroprolactinomas who were treated with BRC.Material and methods: A multicentric study of 29 patients with macroprolactinoma (19 female; 10 males). The mean age was 33 years. The pituitary mass was larger than 10 mm in diameter. There was no endocrinological e...

Introduction: Several studies have incriminated hypomagnesemia in the pathophysiology of diabetes, as the prevalence of this deficit in type 2 diabetics is high, and as it is correlated with glycemic control and chronic diabetic complications.Aims: Studying the prevalence of hypomagnesemia in type 2 diabetics and assessing its impact on quality of life, glycemic control and chronic diabetic complications. Patients and methods: We conducted a descriptive ...

Introduction: The most recent declared pandemic is attributed to COVID-19, caused by the novel coronavirus SARS-CoV-2. The angiotensin-converting enzyme 2, the principal receptor for SARS-CoV-2, exhibits expression in various tissues, prominently within gonadal and hypothalamo-hypophyseal domains. Long COVID, characterized by persistent symptoms post-infection, manifests in certain individuals and includes manifestations associated with the genitourinary system, such as sexual...

Introduction: COVID-19 is a viral infection that can affect various endocrine tissues, including the thyroid. In some patients, symptoms may persist after the infection, defined as Long COVID. Given the similarity of some of these symptoms to those encountered in thyroid disorders, we have decided to assess thyroid function in patients previously infected with SARS-CoV-2.Patients & Methods: This was a prospective study conducted from January to Decem...

Introduction: The metabolic syndrome (MS) is a real public health problem on a global scale. People with MS are at increased risk not only for cardiovascular diseases but also for neoplasia. The aim of our study is to determine the prevalence of MS in patients with digestive neoplasia and to study the impact of MS on the epidemiological, clinical profile and prognosis of digestive neoplasms.Material and methods: This is a retrospective study including pa...

Introduction: Latent autoimmune diabetes in adults (LADA) is a genetically linked, autoimmune form of type 1 diabetes mellitus (DM) that accounts for 2–12% of all cases of diabetes.The goal of our study is to detect LADA among patients who were diagnosed as type 2 DM and who became insulin requiring.Methods: Our study included 45 patients (15 men, 30 women) diagnosed as type 2 DM, who had a poor glycemic control on oral hypogl...